|
Wednesday, March 18 |
|
1:00 pm |
Arrival, registration, media transfer at registration counter
“get together” snacks |
| |
|
2:00
pm |
Opening remarks
G-R Burmester, Andreas Radbruch |
| |
From Pathomechanisms to Cellular Targets
Chair: J.R. Kalden, Erlangen and G.-R. Burmester, Berlin |
| 2:15
pm |
Marcel van den Brink, New York
Off-the-shelf adoptive cell therapy with T cell precursors across
MHC barriers |
| 2:40
pm |
Rick Holmdahl, Stockholm
Therapeutic possibilities interacting with arthritogenic antibodies |
| 3:05 pm |
Steffen Gay, Zürich
Epigenetics in Rheumatic Diseases |
3:30 pm |
Bruno Kyewski, Heidelberg
How central is central tolerance? |
|
3:55 pm |
Coffee break |
| 4:20 pm |
Tobias Bopp, Mainz
Mechanisms of nTreg-mediated suppression |
| 4:45 pm |
Christian Jorgensen, Montpellier
Genetic biomarkers for selected biotherapies in RA |
| 5:10 pm |
Matthias Edinger, Regensburg
Adoptive Treg cell transfer in stem cell transplantation |
| |
B cells and Plasma Cells
Chair: Günter Steiner, Wien and Falk Hiepe, Berlin |
| 5:35 pm |
David Tarlinton, Melbourne
Antagonising Pro-Survival Pathways to Modulate Immune Response |
| 6:00 pm |
Simon Fillatreau, Berlin
Activated B cells in immunity: the case for a regulatory role |
| 6:25 pm |
Reinhard Voll, Erlangen
Plasma cell depletion by proteasome inhibitors in the treatment of lupus-like disease in mice |
| 7:00 pm |
Dinner-Buffet |
| Thursday, March 19 |
| |
Proinflammatory T cells
Chair: Rene van Lier, Amsterdam and Andreas Radbruch, Berlin |
| 9:00 am |
Francesco Annunziato, Florence
Human IL-17-producing cells: origin and development |
| 9:25 am |
Pierre Miossec, France
IL-17 and Th17: contribution to arthritis chronicity |
| 9:50 am |
Hyun-Dong Chang, Berlin
The pro-inflammatory immunological memory |
| 10:15 am |
Ken Smith, Cambridge
A CD8 T cell transcription signature predicts prognosis in autoimmune disease |
| 10:40 am |
Coffee break |
|
Regulatory T cells
Chairs: Reinhold Schmidt, Hannover and Wlodzimierz Maslinski, Warsaw |
| 11:05 am |
Alf Hamann, Berlin
Stability and Epigenetic of Tregs |
| 11:30 am |
Berent Prakken, Utrecht
Regulatory T cells in autoimmunity: good guys, bad guys, or incompetent bystanders? |
| 11:55 pm |
Hans Koenen, Nijmegen
Human regulatory T cell expansion, antigenspecificity and plasticity; lessons learned from allo-antigens |
| 12:20 pm |
Lunch |
|
MSC, NK-cells & other cells
Chair: Thomas Pap, Münster and Ulf Müller-Ladner, Gießen |
| 13:20 pm |
Francesco Dazzi, London
Mesenchymal stem cells and autoimmune disease – part I - the molecular basis for immunosuppression |
| 13:45 pm |
Lorenzo Moretta, Genoa Alloreactive NK cells in the therapy of high risk leukemias |
| 14:10 pm |
Coffee break |
|
Lessons from Clinical Stem Cell Reconstitutions
Chair: Dominique Farge, Paris and Ina Kötter, Tübingen |
| 14:35 pm |
Riccardo Saccardi, Florence
Haematopoietic stem cell transplantation in autoimmune diseases:
The EBMT Experience |
| 15:00 pm |
Dominique Farge, Paris
Long term results of hematopoietic stem cell transplantation: 1996-2008 |
| 15:25 pm |
Renate Arnold, Berlin
Haematopoietic Stem Cell Transplantation in SLE |
| 15:50 pm |
Wietse Kuis, Utrecht
The role of stemcell transplantation and mesenchymal stemcells in pediatric rheumatology |
| 16:15 pm |
Roland Martin, Hamburg
Update on cell therapies in multiple sclerosis
|
| 16:40 pm |
Jaap van Laar, UK
Risks and benefits of stem cell transplants, lessons learned in systemic sclerosis |
| 17:05 pm |
Andreas Thiel, Berlin
Immune reconstitution after stem cell transplantation for autoimmunity -
lessons learned? |
| 18:00 pm |
Speakers Dinner |
| Friday, March 20 |
|
Novel Concepts of Cell-Based Therapies
Chair: Dietger Niederwieser, Leipzig and Hans-Dieter Volk, Berlin |
| 9:00 am |
Alexander Scheffold, Bergisch-Gladbach
Self-limitation of proinflammatory T cells as therapeutic strategy |
| 9:25 am |
Alan Tyndall, Basel
Mesenchymal stem cells and autoimmune disease – part II - animal models and translational programs |
| 9:50 am |
Petra Reinke, Berlin
Adoptive T cell therapy - chance and challenges |
| 10:15 am |
Coffee break |
| 10:40 am |
Hans-Dieter Volk, Berlin
Crosstalk between stem cells and immune cells
|
| 11:05 am |
Birgit Sawitzki, Berlin
Transfer of alloantigen specific Tregs to prevent rejection of allogeneic Transplants |
| 11:30 am |
Andreas Grützkau, Berlin
To be on the safe side: Multiparametric immunophenotyping of peripheral blood cells for monitoring of cell-based therapies |
|
European Perspectives
Chair: Andreas Radbruch, Berlin and Ulf Wagner, Leipzig |
| 11:55 am |
Arnd Hoeveler, Brussels
EC Research, Directorate Health, Head of Unit Biotechnology
Perspectives for cell-based immunotherapies |
| 12:30 pm |
Lunch |